EMBRYO GLUE - Understanding Embryo Glue

In the field of assisted reproductive technology, numerous techniques and advancements have been made to enhance the success rates of In-vitro Fertilization (IVF). One such development is the utilization of embryo glue, a specialized solution used during embryo transfer procedures. In this blog post, we will delve into the details of embryo glue, its composition, benefits and the process of using it during IVF.

‍

Book an Appointment with Dr. Bhavna Banga for all your Fertility concerns

‍

A. Understanding Embryo Glue

‍

‍

Embryo glue, also known as the embryo transfer medium, is a specially formulated solution designed to improve the embryo's chances of implantation during IVF. It serves as a temporary adhesive and provides a nurturing environment for the embryo.

B. Composition of Embryo Glue

The exact composition of embryo glue may vary depending on the manufacturer. However, it typically contains substances that mimic the natural conditions of the uterus, creating an optimal environment for embryo implantation. The components commonly found in embryo glue include:

• Hyaluronan: This is a naturally occurring glycosaminoglycan that aids in the formation of the extracellular matrix, promoting embryo adhesion.
• Albumin: Human serum albumin acts as a stabilizer and provides essential nutrients to support embryo development.
• Heparin: This anticoagulant substance prevents clotting and promotes blood flow, improving the embryo's chances of implantation.
• Vitamins and amino acids: These provide additional nourishment to the embryo during the crucial implantation phase.

C. Benefits of Using Embryo Glue

The application of embryo glue during IVF procedures offers several potential advantages, including:

• Enhanced embryo-endometrium interaction: The adhesive properties of the glue facilitate better attachment of the embryo to the uterine lining, increasing the chances of successful implantation.
• Reduced embryo displacement: Embryo glue helps keep the embryo in place, minimizing the risk of its displacement during and after transfer.
• Improved implantation rates: Studies have suggested that the use of embryo glue may lead to higher implantation rates and improved pregnancy outcomes.
• Potential for frozen embryo transfers (FET): Embryo glue can also be used during FET cycles to enhance the implantation of thawed embryos.

‍

Must Read : FET – Frozen Embryo Transfer & Impacts

‍

D. The Process of Using Embryo Glue

The application of embryo glue is typically incorporated into the embryo transfer procedure. Here's a step-by-step overview:

• Selection of the embryo: The embryologist selects the most viable embryo(s) based on specific criteria, such as morphology and developmental stage.
• Preparation of the catheter: The embryo glue solution is drawn into the embryo transfer catheter.
• Loading the embryo: The selected embryo(s) are carefully loaded into the catheter containing the embryo glue.
• Transfer procedure: The physician guides the catheter through the cervix into the uterus, placing the embryo(s) at the desired location within the uterine cavity.
• Confirmation and removal: The catheter is checked to ensure successful embryo transfer, and then gently removed.
• Post-transfer care: After the procedure, the patient is typically advised to rest for a short period before resuming normal activities.

Conclusion

Embryo glue is an innovative tool used during IVF procedures to improve embryo implantation rates. By creating an environment that mimics the natural conditions of the uterus, embryo glue offers potential benefits such as enhanced embryo-endometrium interaction, reduced embryo displacement and improved implantation rates. As the field of assisted reproductive technology continues to advance, embryo glue represents a promising development that can contribute to increased success rates in fertility treatments.

‍

‍