Sperm DNA Fragmentation Test

The Integrity of sperm DNA is being recognized as an important factor for successful reproductive outcomes. Sperm DNA fragmentation testing offers a better diagnostic and prognostic value than routine semen analysis. By using Sperm Chromatin (SCD) Test, the DNA fragmentation can be accurately measured under a conventional bright-field microscopy. The SCD test is a simple, reliable and reproducible technique.

What is DNA Fragmentation??

  • DNA fragmentation is the breaking of DNA strands into pieces.
  • It is estimated that 25% infertile men have higher level of Sperm DNA fragmentation.
  • Approximately 10% normal Semen Analysis may have elevated levels of DNA fragmentation.
  • Men with poor semen parameters have high levels of DNA fragmentation.

Consequences of DNA Fragmentation

  • Causes Male Infertility.
  • Unsuccessful IUI/IVF .
  • Impaired rates of fertilization (both in vivo / in vitro).
  • Impaired/ arrested embryo development.
  • Miscarriages.
  • Dominant genetic diseases.
  • 80% of couples with diagnosis of IDIOPATHIC infertility have sperm DNA damage.