Preimplantation genetic testing (PGT) is a pair of twin procedures that check for genetic defects in embryos created through in vitro fertilisation (IVF) technology. The PGT umbrella is composed of preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD).
Preimplantation Genetic Testing
PGS is a method that screens embryos of chromosomally normal genetic parents, for structural or numerical chromosomal anomalies.
Preimplantation Genetic Diagnosis
PGD is performed to trace potential embryonic defects in couples where one or both partners have a known genetic abnormality. The procedure is capable of detecting sex-linked disorders, single gene defects and chromosomal disorders.
Advantages of Preimplantation Genetic Testing Technology
Elimination of Genetic Predisposition
PGT works like a sieve, eliminating embryos that carry unfavourable chromosomal properties. It is especially useful for couples who want to prevent existing genetic conditions from being passed on.
Practical Decision Making
Genetic testing is commonly favoured over conventional post-conception diagnostic procedures which often entail difficult decision making surrounding potential pregnancy termination.