Preimplantation Genetic Screening (PGS)

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What Is Preimplantation Genetic Testing?

Preimplantation genetic testing is a bipartite process that allows an embryologist to sift through embryos created via IVF, for genetic defects. The system offers two diverse, revolutionary methods for testing. The first, is preimplantation genetic screening (PGS), a technique that evaluates embryos of chromosomally normal genetic parents for structural or numerical chromosomal errors. The second method is preimplantation genetic diagnosis (PGD), a tool that highlights anomalies in embryos whose parents have a known history of genetic abnormalities. PGD can uncover sex-linked disorders, single gene defects and chromosomal disorders.

Why Choose Preimplantation Genetic Testing?

Preimplantation genetic testing tools present several advantages for hopeful parents, promoting only healthy embryos that are likely to succeed.

Detection of Genetic Disorders

Genetic testing tools like preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD) can provide a keyhole into genetic diseases that may have been inherited by an embryo. The technology allows embryologists to handpick the embryos with the lowest risk of acquiring a chromosomal abnormality. This twin-procedure can be a welcome proposition for couples who have a history of inherited conditions.

Reduced Risk of Multiple Births

By selecting embryos that are most likely to thrive in a uterine environment, your embryologist can minimise the risk of multiple births. On Cloudnine, our safety norms are tethered to our philosophy of promoting happy, healthy pregnancies. Hence, we limit the number of embryos transferred to two, per in vitro fertilisation (IVF) cycle.

Is Preimplantation Genetic Testing Right for Me?

Preimplantation genetic testing is suited for couples where one or both partners are carriers of sex-linked disorders or genetic or chromosomal abnormalities. The procedure is also useful for women who are over 35 years old, or those who have experienced failed fertility treatments or recurrent miscarriages.

What Are the Steps of Preimplantation Genetic Testing?

Preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) are parallel procedures that follow similar steps.

1

Cell Retrieval

First, a pair of cells is extracted from each multi-cell embryo.

2

Cell Evaluation

Once several pairs of cells are gathered, each set is examined to gauge the potential presence of an abnormal gene in the corresponding embryo.

3

Embryo Transfer

Following the selection of the best embryos from the cell evaluation routine, your embryologist will transfer up to two embryos to your uterus for implantation.

4

Cryopreservation of Additional Embryos

There are often embryos left over after embryos are transferred to the uterus. On Cloudnine, we offer advanced cryopreservation facilities that allow you to freeze your surplus embryos for use in future in vitro fertilisation (IVF) cycles. Cryopreserved embryos can be used for up to ten years.

What Are the Risks of Preimplantation Genetic Testing?

Genetic testing can prove to be inaccurate if inadequate attention to detail is given. The specialist team on Cloudnine aims to maximise the success rate of genetic screening and diagnosis by carefully engineering every step of the process.

False Negatives

Several global examples of genetic testing have been spotlighted for having produced imprecise results. Smaller clinics that do not possess the expertise to carry out genetic testing run the risk of transferring abnormal embryos to the uterus, owing to false negative results. The Cloudnine gold-standard strives for continual accuracy, offering you the best outcome, always.

TESTIMONIALS

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Cloudnine Helped Us Realise Our Long-Held Dream of Parenthood.
Dr. Radhika Sheth was our pillar of strength throughout our days of infertility. When we consulted her, she suggested that my wife and I pursue fertility treatment on Cloudnine. Cloudnine gave us the best of both worlds; the comfort of consulting Dr. Sheth and easy access to first-class amenities. Over the span of 4 months, we underwent 6 treatment cycles in order to beat our stubborn condition. And in the end, our persistence paid off. Thanks to Dr. Sheth, we conceived. We were so content with our experience, that we opted to continue our affiliation to Cloudnine with their signature maternity experience. After all, Cloudnine helped us realise our long-held dream of parenthood.

Mr. Amit Kumar
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My fertility treatment plan on Cloudnine was composed of an HSG test followed by two IVF cycles. The experience was very good, and if it weren’t for the support and encouragement I received from the doctors and nurses, I wouldn’t have become a mother to my baby boy. I am thankful to Cloudnine for giving me the gift of motherhood.

Mrs Meena
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I was referred to Dr. Uma Maheshwari early this year. At the outset, it was an emotional experience, but Dr. Maheshwari and all the nurses, especially Divya, Omana and Ranjitha, were warm and embraced me like they would, family. Dr. Uma was very caring and always remembered every little detail about my pregnancy. Best of all, she was available when we needed her.
I consider Cloudnine a very lucky place. I came here looking to go through fertility procedures and artificial conception but ended up conceiving naturally. I would recommend Dr. Maheshwari and her entire team to those looking for quality fertility solutions. Thanks to the entire team for taking such good care of me.

Mrs Rakshambi Kai K
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I opted to meet Dr. Radhika Sheth at Cloudnine Hospital, Malad, to discuss fertility treatment options. I knew I’d made the right choice when I discovered how approachable she was. She was very cooperative, always available, ever-smiling and full of positive energy. Not only did she suggest the right treatment plan for me, she worked hard to make me feel special along the way.

Mrs Shruti Pansari
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I am extremely pleased with the experience we had with Dr. Radhika Sheth. After having undergone fruitless fertility treatments for more than two years with other doctors, I was finally able to conceive after an IVF cycle administered by Dr. Sheth. Needless to say, she was very helpful and supportive throughout my treatment tenure. I am and always will be eternally thankful to Dr. Sheth for giving me my precious bundle of joy.

Mrs. Bhumika Vashisth
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I am extremely happy with the treatment we received from Dr. Radhika Sheth and her team at Cloudnine Clinic. The doctor devoted ample time to hearing about our medical history, present problems and general issues we were facing. She was very understanding and would patiently answer all the questions we asked her. During the first visit itself, Dr. Sheth assured us that we would get pregnant; that there was absolutely no doubt about it. Hearing those words was a big relief and instantly boosted our confidence. We started our fertility treatment last year, after which, much to our delight, we finally conceived. We are eagerly awaiting our baby now and can hardly express our happiness in words. We consider ourselves very lucky that God directed us to Cloudnine Clinic.
Thanks to Dr. Radhika Sheth and her entire team for making our journey to conception worthwhile. Last but not the least, a big thumbs up to all the administration staff for the wonderful operational support.

Mrs Vaishnavi Ghosalkar
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I am very happy to share experience I had with Sure. I tried to conceive from past 1 year without any success. I had gone to many doctors in Bangalore and at my hometown but I couldn’t conceive. I came to know about Sure from Cloudnine hospital. I had posted a message for appointment and I immediately got a call from Sure. I was amazed with their immediate response. This experience continued. I got an appointment with Dr. Jyothi Menon and was very much satisfied with her answers during my first visit itself. I got confidence with her words. Based on her advice, we thought of going for a treatment at Sure. Her way of treatment was very good. We had to visit Sure 4-5 times in the first cycle. My first cycle at Sure was successful. I am 3 months pregnant now. I am very thankful to Dr. Jyothi Menon. Staff at sure are really caring, supportive and are cool in answering all the questions. Especially I need to mention about Swetha at reception. I had very good experience with her every time I go there. Ambience at sure is very good and hygienic. Nursing staff is also very caring.Overall it was a wonderful experience.

Mrs. Asha
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Doctor was available as per the appointment which is very much appreciated. Doctor spoke to us in a very encouraging manner and presented the facts clearly. Support staffs were very polite and responded to situation. GREAT SERVICE!

Mrs. Harini
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The team is fantastic, very co-operative and knows their jobs. At OT sister Shyamala was at most courteous, understanding by sharing her love and affection to me. The admin team is well managed and carry their duties effectively GRE-Geetha and others. The other nurses Sangeetha, Sherly others whose name I am not able to recollect were very good especially while injections. Overall very impressed with the setup and have started referring people.

Mrs. Jaya
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It was a wonderful experience, I am very glad with the way all the doctors, nurses have supported me. Hope to see the clinic grow bigger and maintain its reputation throughout. Thanks to all of you and I hope to come back as a ‘MOM’.

Mrs. Payal

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