Preimplantation Genetic Screening (PGS)

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What Is Preimplantation Genetic Testing?

Preimplantation genetic testing is a bipartite process that allows an embryologist to sift through embryos created via IVF, for genetic defects. The system offers two diverse, revolutionary methods for testing. The first, is preimplantation genetic screening (PGS), a technique that evaluates embryos of chromosomally normal genetic parents for structural or numerical chromosomal errors. The second method is preimplantation genetic diagnosis (PGD), a tool that highlights anomalies in embryos whose parents have a known history of genetic abnormalities. PGD can uncover sex-linked disorders, single gene defects and chromosomal disorders.

Why Choose Preimplantation Genetic Testing?

Preimplantation genetic testing tools present several advantages for hopeful parents, promoting only healthy embryos that are likely to succeed.

Detection of Genetic Disorders

Genetic testing tools like preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD) can provide a keyhole into genetic diseases that may have been inherited by an embryo. The technology allows embryologists to handpick the embryos with the lowest risk of acquiring a chromosomal abnormality. This twin-procedure can be a welcome proposition for couples who have a history of inherited conditions.

Reduced Risk of Multiple Births

By selecting embryos that are most likely to thrive in a uterine environment, your embryologist can minimise the risk of multiple births. On Cloudnine, our safety norms are tethered to our philosophy of promoting happy, healthy pregnancies. Hence, we limit the number of embryos transferred to two, per in vitro fertilisation (IVF) cycle.

Is Preimplantation Genetic Testing Right for Me?

Preimplantation genetic testing is suited for couples where one or both partners are carriers of sex-linked disorders or genetic or chromosomal abnormalities. The procedure is also useful for women who are over 35 years old, or those who have experienced failed fertility treatments or recurrent miscarriages.

What Are the Steps of Preimplantation Genetic Testing?

Preimplantation genetic diagnosis (PGD) and preimplantation genetic screening (PGS) are parallel procedures that follow similar steps.

1

Cell Retrieval

First, a pair of cells is extracted from each multi-cell embryo.

2

Cell Evaluation

Once several pairs of cells are gathered, each set is examined to gauge the potential presence of an abnormal gene in the corresponding embryo.

3

Embryo Transfer

Following the selection of the best embryos from the cell evaluation routine, your embryologist will transfer up to two embryos to your uterus for implantation.

4

Cryopreservation of Additional Embryos

There are often embryos left over after embryos are transferred to the uterus. On Cloudnine, we offer advanced cryopreservation facilities that allow you to freeze your surplus embryos for use in future in vitro fertilisation (IVF) cycles. Cryopreserved embryos can be used for up to ten years.

What Are the Risks of Preimplantation Genetic Testing?

Genetic testing can prove to be inaccurate if inadequate attention to detail is given. The specialist team on Cloudnine aims to maximise the success rate of genetic screening and diagnosis by carefully engineering every step of the process.

False Negatives

Several global examples of genetic testing have been spotlighted for having produced imprecise results. Smaller clinics that do not possess the expertise to carry out genetic testing run the risk of transferring abnormal embryos to the uterus, owing to false negative results. The Cloudnine gold-standard strives for continual accuracy, offering you the best outcome, always.

TESTIMONIALS

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They say, ‘Never lose Hope’

Dr. Manju Nair was my doctor here at Cloudnine. I have a 9-year-old daughter but could not conceive for the 2nd time. After coming to Cloudnine not only were my spirits uplifted but my hope of conceiving after these many years turned into reality 🙂

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Positivity spread across to enlighten our hearts

It was a good experience at Cloudnine. Dr. Uma is one of the best doctors in the city. She was very understanding of our situation and gave us a consultation in a very calm manner with much clarity. The atmosphere in Cloudnine is very positive and welcoming.

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The touch of genuine care

The doctor assigned to us showed genuine care towards us and provided the best opinion, Dr. Uma explained all the processes involved with complete compassion. The environment was very comfortable. We give credit to cloudnine for this impressive treatment.

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A great experience in making

The staff was immensely supportive, right from the support-desk staff, the nurses, to the doctors. I was guided and helped wholeheartedly. The entire team equally contributed to this great experience. I thank you all for it.

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Dr. Manju Nair Has a Divine Persona

 

I don’t have enough words to describe Dr. Manju Nair’s qualities adequately. She is simply the best. She is confident, caring, friendly, positive and has some kind of magic in her hands. Among all the fertility specialists we met, she shone through with her divine persona. Dr. Nair’s vibrant personality made us feel comfortable and I thank her and her team for the wonderful care they took at every step of our treatment. Hats off to them all!

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Dr. Manju Nair Is the Friendliest Doctor We Have Ever Met

This past year has been a wonderful journey for us. Dr. Manju Nair has helped us navigate highs and lows, and is the most honest and friendly doctor we have ever met. ‘Thank you’ doesn’t quite encapsulate the gratitude we have for her, and we are indebted to her for all she has done for us.

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Coming to Cloudnine Fertility, Old Airport Road Was the Best Decision of My Life

I think I made the best decision of my life by coming to Cloudnine Fertility, Old Airport Road and meeting Dr. Manju Nair. She listened to my concerns with immense patience and calmed my fears about the scans I would have to undergo on my way to conception. A big thanks to her for tolerating the fuss and frenzy I inevitably made during each scan. Dr. Nair proposed a wonderful fertility treatment, due to which, I have now conceived twins. My husband, my family and I are grateful to her, and I would recommend any couple struggling to conceive, to meet her. Also, a big thanks to the support staff for being so considerate and taking such good care of me!

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Dr. Uma Maheshwari Cocooned Us In Comfort and Positivity

We had a great experience at Cloudnine Fertility, Jayanagar. Dr. Uma Maheshwari was very calm throughout our treatment and cocooned us in comfort and positivity. The counselling we received was excellent.
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Dr. Uma Maheshwari Genuinely Cares About Each Couple

Dr. Uma Maheshwari genuinely cares about each couple, and provided us with valuable guidance through our infertility treatment. She explained every aspect of the cycle to us. Overall, we found Cloudnine Fertility, Jayanagar to be a comforting environment with the best selection of treatments.
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Our Experience at Cloudnine Fertility, Jayanagar Was Good!

We found the staff at Cloudnine Fertility, Jayanagar very supportive. They guided us wonderfully through the various steps of our treatment. The front desk staff was highly cooperative. Our overall experience was good. Thanks to the whole team!
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