DNA Fragmentation Index Of Sperm (DFI)

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What Is DNA Fragmentation Index of Sperm (DFI)?

The quality and integrity of your sperm are vital factors in determining its motility, concentration and morphology. However, DNA fragmentation can damage sperm, and can be a contributor of subfertility and infertility. DNA fragmentation index (DFI) is a superior diagnostic and prognostic tool used to evaluate the degree of fragmentation of sperm. The procedure offers far better results than traditional tests, detecting details that reach beyond conventional methods.

Why Choose to Calculate DNA Fragmentation Index of Sperm?

DNA fragmentation index (DFI) is something that should be considered if infertility or subfertility of the male partner is suspected.

Early Diagnosis

Sperm DNA fragmentation provides a clear picture of the viability of sperm based on the integrity of its DNA. An early diagnosis can prevent unwanted stress and worry, with your fertility consultant personalising a treatment plan for you.

Unfavourable Outcomes of Fragmented Sperm

By opting to seek a diagnosis, and subsequently, a treatment plan, you can save yourself from unfavourable outcomes usually associated with fragmented sperm. Sperm fragmentation has been found to lead to miscarriages and chromosomal abnormalities in offspring, amongst other risks.

Is Calculating DNA Fragmentation Index of Sperm Right for Me?

With a rise of reproductive toxicants lurking in various environmental quarters, sperm fragmentation is on an incline. Sperm DNA fragmentation could be a barrier to male fertility. The possibility of fragmented sperm exists even when other attributes like sperm motility, count and morphology are normal. If you and your partner are experiencing difficulty conceiving, consider consulting a fertility specialist to explore the DNA fragmentation index of your sperm (DFI).

What Are the Steps of Calculating DNA Fragmentation Index of Sperm?

The DNA fragmentation index of sperm (DFI) is gauged through a straightforward test, akin to a regular semen evaluation.

1

Semen Procurement

At the outset, a semen sample is obtained from the male partner for examination.

2

Sperm Evaluation

Our specialised team of embryologists evaluates the semen sample by running it through an array of sophisticated diagnostic tests to measure the degree of sperm DNA fragmentation. The condition can be sidestepped with an effective fertility plan. Our fertility specialists will sit down with you and your partner to discuss a suitable solution, should you be diagnosed with sperm DNA fragmentation.

What Are the Risks of Calculating DNA Fragmentation Index of Sperm?

The risks that stem from sperm DNA fragmentation have no bearing on the health of the male partner. There are, however, some perceived limitations of the procedure.

Distinction of DNA

It is understood that only a subset of DNA plays a role in the functioning of the human body. Thus, while an evaluation may indicate fragmentation in certain areas of DNA, these functions may not be relevant at all. However, distinguishing between useful and redundant DNA may prove futile in the fragmentation testing process.

Threshold of DNA Fragmentation

There is no recognised threshold associated with sperm fragmentation. While it is well understood that fertile men demonstrate lower fragmentation levels than subfertile and infertile men, there is still an intersection that is being researched.

TESTIMONIALS

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Dr. Manju Nair was my doctor here at Cloudnine. I have a 9-year-old daughter but could not conceive for the 2nd time. After coming to Cloudnine not only were my spirits uplifted but my hope of conceiving after these many years turned into reality 🙂

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It was a good experience at Cloudnine. Dr. Uma is one of the best doctors in the city. She was very understanding of our situation and gave us a consultation in a very calm manner with much clarity. The atmosphere in Cloudnine is very positive and welcoming.

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The doctor assigned to us showed genuine care towards us and provided the best opinion, Dr. Uma explained all the processes involved with complete compassion. The environment was very comfortable. We give credit to cloudnine for this impressive treatment.

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A great experience in making

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Dr. Manju Nair Has a Divine Persona

 

I don’t have enough words to describe Dr. Manju Nair’s qualities adequately. She is simply the best. She is confident, caring, friendly, positive and has some kind of magic in her hands. Among all the fertility specialists we met, she shone through with her divine persona. Dr. Nair’s vibrant personality made us feel comfortable and I thank her and her team for the wonderful care they took at every step of our treatment. Hats off to them all!

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Dr. Manju Nair Is the Friendliest Doctor We Have Ever Met

This past year has been a wonderful journey for us. Dr. Manju Nair has helped us navigate highs and lows, and is the most honest and friendly doctor we have ever met. ‘Thank you’ doesn’t quite encapsulate the gratitude we have for her, and we are indebted to her for all she has done for us.

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Coming to Cloudnine Fertility, Old Airport Road Was the Best Decision of My Life

I think I made the best decision of my life by coming to Cloudnine Fertility, Old Airport Road and meeting Dr. Manju Nair. She listened to my concerns with immense patience and calmed my fears about the scans I would have to undergo on my way to conception. A big thanks to her for tolerating the fuss and frenzy I inevitably made during each scan. Dr. Nair proposed a wonderful fertility treatment, due to which, I have now conceived twins. My husband, my family and I are grateful to her, and I would recommend any couple struggling to conceive, to meet her. Also, a big thanks to the support staff for being so considerate and taking such good care of me!

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Dr. Uma Maheshwari Cocooned Us In Comfort and Positivity

We had a great experience at Cloudnine Fertility, Jayanagar. Dr. Uma Maheshwari was very calm throughout our treatment and cocooned us in comfort and positivity. The counselling we received was excellent.
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Dr. Uma Maheshwari Genuinely Cares About Each Couple

Dr. Uma Maheshwari genuinely cares about each couple, and provided us with valuable guidance through our infertility treatment. She explained every aspect of the cycle to us. Overall, we found Cloudnine Fertility, Jayanagar to be a comforting environment with the best selection of treatments.
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Our Experience at Cloudnine Fertility, Jayanagar Was Good!

We found the staff at Cloudnine Fertility, Jayanagar very supportive. They guided us wonderfully through the various steps of our treatment. The front desk staff was highly cooperative. Our overall experience was good. Thanks to the whole team!
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