Intracytoplasmic Sperm Injection (ICSI)

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What Is an Intracytoplasmic Sperm Injection Procedure?

An intracytoplasmic sperm injection (ICSI) routine is usually paired with a conventional in vitro fertilisation (IVF) procedure and is particularly helpful for men who possess a low sperm count or poor sperm motility. It is also suited for men who experience difficulty ejaculating or have undergone a vasectomy in the past. ICSI aims at directly injecting the sperm into the egg to achieve fertilisation. Then, once the resultant embryo is healthy enough to call the uterus its home, it is carefully placed onto the uterine lining. Sometimes, ICSI is enhanced through an additional medical protocol called physiological intracytoplasmic sperm injection (PICSI). PICSI is used to select the best possible sperm for fertilisation during IVF. By picking a superior quality sperm, the odds of fertilisation during IVF increase. PICSI pivots on the concept of Hyaluronan binding. Hyaluronan is a unique material found around an egg; PICSI endeavours to identify sperm that bind well with the hyaluronan around an egg cell.

Why Choose an Intracytoplasmic Sperm Injection Procedure?

An intracytoplasmic sperm injection (ICSI) is ideal for augmenting the fertility of a male partner. It is recommended in multiple scenarios.

Low Sperm Count

By injecting sperm into an egg, ICSI increases the chances of fertilisation for men whose semen is sparsely populated with sperm.

Abnormally Shaped Sperm

Healthy sperm are buttressed by a circular head on one end, and a long, pointed tail on the other. For misshapen sperm, motility could prove to be a problem. Also, even if an abnormally shaped sperm does reach an egg, penetrating through the outer wall of the egg may prove difficult.

Obstruction in the Vasa Deferentia

The vasa deferentia are the fine pipes that carry sperm from the testicles to the urethra. Sometimes, these tubes may be closed, either naturally, or as a result of a vasectomy. In this case, sperm have no way of exiting the testicles. By drawing sperm directly from the testicles and injecting a single sperm cell into an egg, ICSI could optimise the chances of fertilisation, and in turn, of conception.

Is an Intracytoplasmic Sperm Injection Procedure Right for Me?

An intracytoplasmic sperm injection (ICSI) technique can be an ideal addition to a traditional in vitro fertilisation (IVF) procedure. The success of an ICSI routine rests on a variety of factors, including the age of the partners and the fertility problem identified. On Cloudnine, we conduct an exhaustive fertility examination before recommending a fertility treatment to a guest. Our medical specialists first consider your medical history and only then, craft a treatment plan to offer optimal results.

What Are the Steps of an Intracytoplasmic Sperm Injection Procedure?

An intracytoplasmic sperm injection (ICSI) procedure is composed of five main steps.

1

Sperm Collection

First, a semen sample is collected from the male partner. This semen may be organically drawn or obtained via a surgical testicular procedure.

2

Egg Collection

Once a sperm sample has been collected from the male partner, a selection of mature eggs are surgically retrieved from the female partner.

3

Sperm Injection

In this stage, an embryologist carefully injects a single sperm cell into a healthy egg using a hollow needle.

4

Observation

Once an egg and sperm unite, they form a minute embryo, which is cultured in a laboratory for approximately four days. On Cloudnine, our advanced monitoring systems cocoon embryos so that they are continually underpinned by optimal conditions.

5

Implantation

Once an embryo is about four days old, it is gently placed inside the uterus. A few days later, it burrows itself into the uterine lining, a process known as implantation.

What Are the Risks of an Intracytoplasmic Sperm Injection Procedure?

If not done correctly, an intracytoplasmic sperm injection (ICSI) routine can present a handful of risks. On Cloudnine, we take careful measures to ensure that the risks posed by the procedure are mitigated as far as possible.

Damaged Eggs

The egg extraction process could compromise the quality of your eggs. The fertility specialists on Cloudnine take special care to see that the eggs are handled carefully during the retrieval process.

Inadequate Development of Embryo

Despite a successful round of fertilisation, sometimes, an embryo may fail to grow beyond a four-cell entity. On Cloudnine, our embryologists culture multiple embryos to spread this risk. We consistently strive to keep the odds in your favour.

TESTIMONIALS

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We Were Thrilled With the Services Provided on Cloudnine

The ever-smiling Dr. Manju Nair is an excellent fertility specialist, not to mention, extremely polite and courteous. We were thrilled with the services provided to us by her and the team of nurses. The entire treatment process was seamless and we are now blessed with a baby girl! We would like to thank everyone who made our journey on Cloudnine so wonderful!

Cloudnine Fertility Customer
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We Are Grateful to Dr. Manju Nair for Our Little Miracle!

We would like to thank Dr. Manju Nair and the entire team at Cloudnine Fertility from the bottom of our hearts. The staff members extended their absolute support and guided us throughout our journey. It was our life’s best experience! We are extremely grateful to Dr. Nair for our little miracle!

Cloudnine Fertility Customer
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Our IUI Was Successful, Thanks to Dr. Manju Nair

We had a wonderful experience with Dr. Manju Nair at the Cloudnine Fertility Clinic. We underwent an intrauterine insemination (IUI), and Dr. Nair and the entire support staff were very friendly, proactive and understanding at every stage. They took extremely good care of us. The IUI proved successful, and we were finally pregnant by the grace of God and Dr. Manju Nair’s expert treatment – a life update we had been eagerly awaiting. Our gratitude knows no bounds and we would like to thank each person involved in making our journey memorable.

Cloudnine Fertility Customer
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‘Hope Is Born Here’ is an Understatement for Cloudnine

If you ask me, ‘Hope Is Born Here’ is an inadequate tagline for Cloudnine. Dr. Manju Nair turned out to be my angel. She restored my happiness and I would like to thank her from the bottom of my heart. May God bless her, always!

Cloudnine Fertility Customer
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Dr. Manju Nair’s Efforts Were Truly Commendable

Our journey on Cloudnine started through Dr. Jyotshna Madan, who led us to Dr. Manju Nair. At the time, we were struggling with infertility, and Dr. Nair took care to give us a detailed diagnosis, and an explanation of each procedure during our visits. The way she lent her complete support and motivated us along the way was truly commendable. Additionally, she was easily reachable and this was vital for us during our journey. Apart from the treatment itself, the atmosphere on Cloudnine was amazing, as was the hospitality. We would like to thank Dr. Manju Nair and the entire Cloudnine team for everything they have done for us!

 

Cloudnine Fertility Customer
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Dr. Manju Nair Restored Hope and Positivity in My Life

I want to thank Dr. Manju Nair for everything; for bringing positivity into my life. She has restored hope in me and brightened my days, thanks to her successful treatment. She deserves a warm hug and a massive thanks. In addition, I had a lovely experience with the staff on Cloudnine.

Cloudnine Fertility Customer
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My Quick Journey to Conception Is Testament to Dr. Manju Nair’s Treatment Approach

Dr. Manju Nair is an excellent doctor. She made us feel at ease throughout, and allowed us to freely communicate all our problems. Her treatment approach was awesome, and the fact that I conceived so soon after meeting her is testament to that fact.

Cloudnine Fertility Customer
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We Are Grateful to Dr. Manju Nair for Our Little Miracle!

We would like to thank Dr. Manju Nair and the entire team at Cloudnine Fertility from the bottom of our hearts. The staff members extended their absolute support and guided us throughout our journey. It was our life’s best experience! We are extremely grateful to Dr. Nair for our little miracle!

Cloudnine Fertility Customer
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When I Look Back on Our Fertility Struggle, I Wish We Had Met Dr. Manju Nair Sooner

My wife and I had been trying for a baby for almost three years, having consulted at least 3-4 renowned doctors in Bangalore without any success. After two failed intrauterine insemination (IUI) cycles, we were advised a surgical scan. However, we were wary of going under the knife as part of a diagnostic procedure, and decided against it. Shortly afterwards, we met Dr. Manju Nair on Cloudnine, and we were pleased with our first interaction. She tried to understand our history, the tests done so far, and took note of all our past consultations. Then, she recommended some additional tests for my wife and referred me to an andrologist. Once she had our reports, she was able to pinpoint the problem within a few short weeks. Based on the findings, Dr. Nair communicated the most advisable treatment, and left the final decision to us. Given my sperm morphology, the options were limited – it was either surgery for me, or in vitro fertilisation (IVF). The surgical scan we had been recommended at our previous clinic wasn’t required at all. We went for IVF as per Dr. Nair’s suggestion and the procedure was a success. We were amazed when the pregnancy test showed positive. Today, our baby is almost four months old.

We really valued Dr. Nair’s friendliness, approachability, positivity and tell-it-like-it-is attitude. She boosted our confidence, gave us hope, yet, never made any false promises. We always came back feeling good after every consultation. I would definitely recommend Dr. Manju Nair to anyone struggling to conceive. She is the finest doctor we have ever met and we wish her continued success in the future.

When I look back on our fertility struggle of almost 3 years – visiting different doctors, waiting in long queues and undergoing numerous scans – I only wish we had met Dr. Nair sooner.

Cloudnine Fertility Customer
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My Experience on Cloudnine Was Seamless

As my fertility specialist, Dr. Manju Nair was cordial, understanding and super helpful. I couldn’t have asked for a better doctor for consultation! Also, I really appreciated the staff and nurses, who were kind and attentive to all my questions. I only have good things to say about my experience here! Keep up the good work!

Cloudnine Fertility Customer

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